Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 9/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188919 | 0.81 | GRIN2B (0.63) | GRIN2BGRIN1KMT2AMEN1POLB | |
| SCHEMBL22136446 | 0.79 | GRIN2B (0.61) | GRIN2BGRIN1KMT2AMEN1POLB | |
| SCHEMBL6402429 | 0.79 | GRIN2B (0.61) | GRIN2BGRIN1KMT2AMEN1POLB | |
| SCHEMBL456941 | 0.77 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| Hydrochloric Acid SCHEMBL3264848 | 0.77 | GRIN2B (0.59) | GRIN2BGRIN1KMT2AMEN1POLB | |
| SCHEMBL17196594 | 0.77 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL14234187 | 0.77 | GRIN2B (0.66) | GRIN2BGRIN1KMT2AMEN1POLB | |
| SCHEMBL20880146 | 0.76 | LOXL2 (0.52) | GRIN2BGRIN1F2F10PRSS1 | |
| SCHEMBL10804968 | 0.76 | GRIN2B (0.63) | GRIN2BGRIN1KMT2AMEN1POLB | |
| SCHEMBL18938347 | 0.74 | KMT2A (0.61) | GRIN2BGRIN1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382211-A1 | PYRAZOLE-I, 2, 4 -OXAD IAZOLE DERIVATIVES AS S.PHING0SINE-1-PH0SPHATE AGONISTS | Bristol-Myers Squibb Company (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010085584-A1 | PYRAZOLE-I, 2, 4 -OXAD IAZOLE DERIVATIVES AS S.PHING0SINE-1-PH0SPHATE AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-07-29 | — | — | WO | disclosed |