Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253164 | 0.78 | LOXL2 (0.56) | LOXL2F10NOS3NOS1NOS2 | |
| SCHEMBL5154701 | 0.78 | LOXL2 (0.56) | LOXL2F10NOS3NOS1NOS2 | |
| SCHEMBL4253161 | 0.78 | LOXL2 (0.56) | LOXL2F10NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL6743124 | 0.77 | LOXL2 (0.54) | LOXL2F10NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL6743119 | 0.77 | LOXL2 (0.54) | LOXL2F10NOS3NOS1NOS2 | |
| SCHEMBL25447789 | 0.77 | LOXL2 (0.54) | LOXL2F10NOS3NOS1NOS2 | |
| SCHEMBL13238642 | 0.77 | LOXL2 (0.54) | LOXL2F10NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL18300737 | 0.77 | LOXL2 (0.54) | LOXL2F10NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL18300738 | 0.77 | LOXL2 (0.54) | LOXL2F10NOS3NOS1NOS2 | |
| SCHEMBL2570851 | 0.76 | GRIN2B (0.63) | F10GRIN2BGRIN1F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466961-A1 | PROLINAMIDE DERIVATIVE AS THROMBIN INHIBITOR, PREPARATION METHOD AND APPLICATION THEREOF | Li, Min (US) | 2019-04-10 | — | — | EP | disclosed |