SCHEMBL25713147

SCHEMBL25713147

Cc1ccc2cc3cccn3cc2c1-c1nccn1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.37
CYP1A2 P05177 4/20 0.37
CYP2D6 P10635 4/20 0.37
CYP2C9 P11712 4/20 0.37
CYP2C19 P33261 4/20 0.37
L3MBTL1 Q9Y468 4/20 0.37
MAPK9 P45984 1/20 0.36
MAPK10 P53779 1/20 0.36
ALOX15B O15296 2/20 0.33
GAA P10253 1/20 0.33
P2RX4 Q99571 1/20 0.32
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
TP53 P04637 2/20 0.32
LCK P06239 1/20 0.32
KIT P10721 1/20 0.32
SRC P12931 1/20 0.32
ALDH1A1 P00352 3/20 0.32
POLB P06746 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20980458 0.81 MAPK9 (0.37) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL25713155 0.77 MAPK1 (0.43) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL25712718 0.75 NPC1 (0.36) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL25713073 0.73 GRM4 (0.34) GAANPC1RAB9ASMN1; SMN2TP53
SCHEMBL25712736 0.71 CYP3A4 (0.36) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL25712228 0.70 KDM4E (0.33) GAANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL25712678 0.68 MAPK1 (0.43) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL25713077 0.68 KDM4E (0.31) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL25712284 0.67
SCHEMBL24160885 0.66 KDM4E (0.45) CYP3A4L3MBTL1GAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685756-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685756-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OPRD1 CYP3A4 446/4885CYP1A2 1270/4885CYP2D6 2777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.