SCHEMBL2571333

SCHEMBL2571333

CC[Si](CC)(CC)CCc1c(CC[Si](CC)(CC)CC)c(CC[Si](CC)(CC)CC)c2cc3cc4cc5ccccc5cc4cc3cc2c1CC[Si](CC)(CC)CC

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
HTR2A P28223 1/20 0.32
NQO1 P15559 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
ELANE P08246 1/20 0.31
MAPT P10636 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HBB P68871 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10058026 0.89 ALDH1A1 (0.39) ALDH1A1KDM4EGAAHPGDHTR2A
SCHEMBL27843679 0.83 HTR2A (0.37) HTR2A
SCHEMBL28672699 0.82 HTR2A (0.47) ALDH1A1KDM4EGAAHPGDHTR2A
SCHEMBL10057997 0.81 HTR2A (0.40) ALDH1A1KDM4EGAAHPGDHTR2A
SCHEMBL3465872 0.80 ALDH1A1 (0.47) ALDH1A1KDM4EGAAHPGDHTR2A
SCHEMBL3465710 0.77 NPC1 (0.41) ALDH1A1KDM4EGAAHPGDHTR2A
SCHEMBL3466503 0.74 TLR8 (0.46) ALDH1A1KDM4EHPGDMAPTHSD17B10
Ammonia Solution, Strong SCHEMBL29111634 0.74 ALDH1A1 (0.48) ALDH1A1KDM4EGAAHPGDHTR2A
SCHEMBL10057998 0.72 KDM4E (0.37) ALDH1A1KDM4EGAAHPGDCYP1A2
SCHEMBL18270300 0.71 MTNR1A (0.47) CYP1A2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2383273-A1 AROMATIC COMPOUND AND METHOD FOR PRODUCING SAME Sumitomo Chemical Company, Limited (JP) 2011-11-02 EP disclosed