Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12384367 | 0.76 | EPHX2 (0.42) | — | |
| SCHEMBL25707472 | 0.75 | NOS3 (0.34) | — | |
| SCHEMBL25704250 | 0.75 | KCNH2 (0.43) | — | |
| SCHEMBL20346984 | 0.74 | CYP4F2 (0.39) | — | |
| SCHEMBL25721990 | 0.67 | NUDT1 (0.40) | — | |
| SCHEMBL25720693 | 0.67 | — | — | |
| SCHEMBL21025402 | 0.64 | EPHX2 (0.34) | — | |
| SCHEMBL24967869 | 0.61 | EPHX2 (0.34) | — | |
| SCHEMBL116939 | 0.58 | CYP1A2 (0.58) | — | |
| SCHEMBL24967232 | 0.58 | DAO (0.32) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436446-B1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2023-06-07 | — | — | EP | disclosed |