Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | FLT3 | P36888 | 4/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HCK | P08631 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 3/20 | 0.32 |
| ▸ | CSF1R | P07333 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19084436 | 0.77 | MEN1 (0.32) | ADORA2AADORA2BMAPK13MEN1KMT2A | |
| SCHEMBL590272 | 0.77 | KDR (0.43) | NOS3NOS2KDRFLT3NOS1 | |
| SCHEMBL16158053 | 0.72 | MAPT (0.36) | NOS3NOS2KDRABL1SRC | |
| SCHEMBL7850281 | 0.68 | MEN1 (0.46) | KDRFLT3LCKCSF1RKIT | |
| SCHEMBL423714 | 0.68 | PDPK1 (0.41) | KDRFLT3ABL1GAALCK | |
| SCHEMBL31280918 | 0.67 | ALOX5AP (0.35) | KDRFLT3ABL1SRCPIK3CD | |
| SCHEMBL16006511 | 0.67 | HTT (0.35) | NOS3NOS2KDRABL1SRC | |
| SCHEMBL15996052 | 0.67 | PIK3CD (0.33) | NOS3NOS2KDRABL1SRC | |
| SCHEMBL17673728 | 0.67 | NOS3 (0.30) | NOS3NOS2NOS1 | |
| SCHEMBL15995815 | 0.66 | KCNA5 (0.51) | KDRFLT3GAALMNAMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |