Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | TYMS | P04818 | 2/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25723712 | 0.85 | CYP3A4 (0.45) | DUTCYP3A4CYP2C9P2RY2P2RY6 | |
| SCHEMBL25721246 | 0.85 | CYP3A4 (0.45) | DUTCYP3A4CYP2C9P2RY2P2RY6 | |
| SCHEMBL23348830 | 0.81 | CYP3A4 (0.72) | DUTCYP3A4CYP2C9P2RY2P2RY6 | |
| SCHEMBL20058991 | 0.81 | CYP3A4 (0.72) | DUTCYP3A4CYP2C9P2RY2P2RY6 | |
| SCHEMBL22348837 | 0.78 | POLB (0.55) | DUTP2RY2P2RY6TYMSP2RY4 | |
| SCHEMBL13063520 | 0.77 | CYP3A4 (0.51) | DUTCYP3A4CYP2C9P2RY2P2RY6 | |
| SCHEMBL19187615 | 0.77 | CYP3A4 (0.46) | CYP3A4CYP2C9P2RY2P2RY6P2RY14 | |
| SCHEMBL111346 | 0.76 | DUT (0.55) | DUTCYP3A4CYP2C9P2RY2P2RY6 | |
| SCHEMBL25714956 | 0.76 | CYP3A4 (0.45) | DUTCYP3A4CYP2C9P2RY2P2RY6 | |
| SCHEMBL25724478 | 0.76 | CYP3A4 (0.45) | DUTCYP3A4CYP2C9P2RY2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |