Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | DUT | P33316 | 3/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25723712 | 1.00 | CYP3A4 (0.45) | CYP3A4CYP2C9DUTP2RY6P2RY2 | |
| SCHEMBL25724478 | 0.89 | CYP3A4 (0.45) | CYP3A4CYP2C9DUTP2RY6P2RY2 | |
| SCHEMBL25714956 | 0.89 | CYP3A4 (0.45) | CYP3A4CYP2C9DUTP2RY6P2RY2 | |
| SCHEMBL25727013 | 0.88 | CYP3A4 (0.41) | CYP3A4CYP2C9DUTP2RY6P2RY2 | |
| SCHEMBL24547486 | 0.87 | MEN1 (0.37) | CYP3A4CYP2C9DUTP2RY6P2RY2 | |
| SCHEMBL25714223 | 0.85 | DUT (0.49) | CYP3A4CYP2C9DUTP2RY6P2RY2 | |
| SCHEMBL13660249 | 0.81 | CYP3A4 (0.60) | CYP3A4CYP2C9DUTP2RY6P2RY2 | |
| SCHEMBL25720876 | 0.80 | DUT (0.38) | CYP3A4CYP2C9DUTP2RY6P2RY2 | |
| SCHEMBL25722152 | 0.80 | DUT (0.38) | CYP3A4CYP2C9DUTP2RY6P2RY2 | |
| SCHEMBL25727731 | 0.80 | DUT (0.38) | CYP3A4CYP2C9DUTP2RY6P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |