Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715802 | 0.82 | PIK3CD (0.38) | PIK3CDFGFR1FGFR3ACVRL1TNK2 | |
| SCHEMBL64680 | 0.77 | ALDH1A1 (0.42) | PIK3CDACVRL1 | |
| SCHEMBL14531415 | 0.74 | ACVRL1 (0.43) | PIK3CDFGFR1FGFR3ACVRL1 | |
| SCHEMBL19377540 | 0.73 | HTT (0.42) | PIK3CD | |
| SCHEMBL14488780 | 0.73 | ACVRL1 (0.52) | PIK3CDACVRL1 | |
| SCHEMBL16021704 | 0.73 | ACVRL1 (0.45) | PIK3CDACVRL1 | |
| SCHEMBL25714863 | 0.72 | MAP4K4 (0.41) | ACVRL1TNK2CSNK2A2CSNK2A1XDH | |
| SCHEMBL27993999 | 0.72 | ACVRL1 (0.33) | PIK3CDFGFR1FGFR3ACVRL1TNK2 | |
| SCHEMBL25715553 | 0.71 | CYP11B1 (0.45) | ACVRL1TNK2 | |
| SCHEMBL28344321 | 0.71 | ALDH1A1 (0.41) | PIK3CDCSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |