Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BLK | P51451 | 3/20 | 0.46 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715709 | 0.88 | BTK (0.48) | F2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25715699 | 0.81 | FGFR1 (0.46) | NPC1RAB9ABLKERBB4KDR | |
| SCHEMBL25715685 | 0.76 | PIK3CD (0.43) | MEN1KMT2ABLKERBB4KDR | |
| SCHEMBL25715748 | 0.76 | POLB (0.41) | MEN1KMT2ABLKERBB4KDR | |
| SCHEMBL3365984 | 0.74 | RAB9A (0.83) | F2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25715555 | 0.70 | SRC (0.41) | NPC1RAB9AMEN1KMT2ABLK | |
| SCHEMBL17584945 | 0.69 | BTK (0.78) | BLKERBB4KDRLCKBTK | |
| SCHEMBL25714868 | 0.69 | KDR (0.39) | BLKERBB4KDRPLK4AURKA | |
| SCHEMBL25715611 | 0.69 | TNK2 (0.38) | MEN1KMT2ABLKERBB4KDR | |
| SCHEMBL29611667 | 0.68 | RAB9A (0.76) | F2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |