Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 6/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715809 | 0.82 | PIK3CD (0.36) | ACVRL1PIK3CDFGFR1FGFR3TNK2 | |
| SCHEMBL23337779 | 0.78 | FGFR1 (0.34) | ACVRL1PIK3CDFGFR1FGFR3TNK2 | |
| SCHEMBL25557835 | 0.74 | FGFR1 (0.33) | ACVRL1PIK3CDFGFR1PDE5A | |
| SCHEMBL23861738 | 0.74 | AURKB (0.36) | PIK3CDFGFR1PDE5A | |
| SCHEMBL25715810 | 0.73 | FGFR1 (0.42) | FGFR1FGFR3 | |
| SCHEMBL25715804 | 0.71 | PIK3CD (0.31) | ACVRL1PIK3CDFGFR1FGFR3 | |
| SCHEMBL25715512 | 0.68 | FGFR1 (0.34) | ACVRL1PIK3CDFGFR1FGFR3 | |
| SCHEMBL15244317 | 0.67 | PDGFRB (0.35) | — | |
| SCHEMBL25557842 | 0.65 | FGFR2 (0.32) | FGFR3TNK2 | |
| SCHEMBL23337825 | 0.64 | FGFR1 (0.37) | ACVRL1PIK3CDFGFR1FGFR3TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |