Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715810 | 0.83 | FGFR1 (0.42) | PLK4AURKADAPK3ROCK2PAK4 | |
| SCHEMBL25715833 | 0.82 | ADK (0.39) | TNK2PLK4AURKADAPK3ROCK2 | |
| SCHEMBL25715807 | 0.82 | ACVRL1 (0.34) | PIK3CDACVRL1TNK2FGFR1FGFR3 | |
| SCHEMBL23337779 | 0.74 | FGFR1 (0.34) | PIK3CDACVRL1TNK2FGFR1FGFR3 | |
| SCHEMBL23861738 | 0.72 | AURKB (0.36) | PIK3CDAURKAABL1NTRK1LCK | |
| SCHEMBL25557835 | 0.70 | FGFR1 (0.33) | PIK3CDACVRL1ABL1FGFR1 | |
| SCHEMBL25715555 | 0.70 | SRC (0.41) | TNK2PLK4AURKADAPK3ROCK2 | |
| SCHEMBL25715486 | 0.69 | FGFR1 (0.44) | ACVRL1TNK2PLK4AURKADAPK3 | |
| SCHEMBL25715515 | 0.69 | FGFR1 (0.62) | FGFR1FGFR3 | |
| SCHEMBL22696564 | 0.65 | RIPK1 (0.37) | TNK2PLK4AURKADAPK3ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |