Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25714215 | 0.83 | FGFR1 (0.34) | PIK3CDFGFR1FGFR3XDHACVRL1 | |
| SCHEMBL25715512 | 0.79 | FGFR1 (0.34) | PIK3CDFGFR1FGFR3XDHACVRL1 | |
| SCHEMBL19697994 | 0.73 | ACVRL1 (0.32) | PIK3CDACVRL1 | |
| SCHEMBL27993999 | 0.72 | ACVRL1 (0.33) | PIK3CDFGFR1FGFR3XDHACVRL1 | |
| SCHEMBL25715807 | 0.71 | ACVRL1 (0.34) | PIK3CDFGFR1FGFR3ACVRL1 | |
| SCHEMBL25714865 | 0.70 | PIK3CD (0.39) | PIK3CDFGFR1FGFR3XDHACVRL1 | |
| SCHEMBL279456 | 0.69 | FGFR1 (0.34) | PIK3CDFGFR1FGFR3XDHACVRL1 | |
| SCHEMBL10118032 | 0.69 | RET (0.37) | FGFR1FGFR3XDHACVRL1 | |
| SCHEMBL25715802 | 0.69 | PIK3CD (0.38) | PIK3CDFGFR1FGFR3XDHACVRL1 | |
| SCHEMBL25715554 | 0.68 | SRC (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |