Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HSF1 | Q00613 | 2/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30464286 | 1.00 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2POLBPKM | |
| SCHEMBL26111733 | 0.84 | HSF1 (0.64) | RAB9ANPC1SMN1; SMN2POLBPKM | |
| SCHEMBL30597751 | 0.84 | HSF1 (0.64) | RAB9ANPC1SMN1; SMN2POLBPKM | |
| SCHEMBL25715073 | 0.84 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2POLBPKM | |
| SCHEMBL26136510 | 0.81 | HSF1 (0.60) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL30597799 | 0.81 | HSF1 (0.60) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL30597718 | 0.79 | MAPT (0.66) | RAB9ANPC1SMN1; SMN2POLBPKM | |
| SCHEMBL26110426 | 0.79 | MAPT (0.66) | RAB9ANPC1SMN1; SMN2POLBPKM | |
| SCHEMBL30464298 | 0.78 | HSF1 (0.73) | RAB9ANPC1SMN1; SMN2POLBPKM | |
| SCHEMBL25715824 | 0.78 | HSF1 (0.73) | RAB9ANPC1SMN1; SMN2POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111005-A1 | CARBOXAMIDE SUBSTITUTED HETEROAROMATIC COMPOUNDS FOR TREATING CANCER | WMT AG (DE) | 2023-06-22 | — | — | WO | disclosed |