Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | BLM | P54132 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 2/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17217159 | 0.82 | PTPN11 (0.37) | PTPN11MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4830150 | 0.73 | PTPN11 (0.54) | PTPN11MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21712348 | 0.71 | CA12 (0.49) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9979780 | 0.69 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL367773 | 0.69 | PTPN11 (0.44) | PTPN11MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9429312 | 0.69 | PTPN11 (0.44) | PTPN11MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9927302 | 0.69 | PTPN11 (0.44) | PTPN11MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22529352 | 0.69 | PTPN11 (0.68) | PTPN11MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2726241 | 0.69 | PTPN11 (0.44) | PTPN11MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL168169 | 0.67 | KDM4E (0.41) | PTPN11MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9837613-B2 | Conjugated polymers | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-9837613-B2 | Conjugated polymers | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-9153784-B2 | Conjugated polymers | MERCK PATENT GMBH (DE) | 2015-10-06 | — | — | US | disclosed |
| US-9153784-B2 | Conjugated polymers | MERCK PATENT GMBH (DE) | 2015-10-06 | — | — | US | disclosed |
| US-20150270490-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20150270490-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| EP-2611851-B1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2014-10-29 | — | — | EP | disclosed |
| US-20130161567-A1 | CONJUGATED POLYMERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-27 | — | — | US | disclosed |
| US-20130161567-A1 | CONJUGATED POLYMERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-27 | — | — | US | disclosed |
| WO-2012028246-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150270490-A1 | CONJUGATED POLYMERS | OCIAD2, PARG, PPOX | PTPN11 2609/4885MAPT 388/4885ALDH1A1 1012/4885 |
| US-20130161567-A1 | CONJUGATED POLYMERS | OCIAD2, PARG, PPOX | PTPN11 2609/4885MAPT 388/4885ALDH1A1 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.