Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAX | P61244 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 3/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16547258 | 0.86 | KDM4E (0.42) | MAPTKDM4ERPS6KB2MYCMAX | |
| SCHEMBL11995959 | 0.86 | ACHE (0.43) | MAPTKDM4ERPS6KB2MYCMAX | |
| SCHEMBL2449714 | 0.85 | KDM4E (0.68) | MAPTKDM4ERPS6KB2NQO2PDGFRB | |
| SCHEMBL29489945 | 0.85 | NQO2 (0.62) | MAPTKDM4ERPS6KB2MYCMAX | |
| SCHEMBL2368230 | 0.85 | NQO2 (0.57) | MAPTKDM4ERPS6KB2NQO2PGK1 | |
| SCHEMBL2367850 | 0.85 | NQO2 (0.62) | MAPTKDM4ERPS6KB2MYCMAX | |
| SCHEMBL9979779 | 0.83 | EGFR (0.42) | MAPTKDM4ERPS6KB2MYCMAX | |
| SCHEMBL15581107 | 0.83 | KDM4E (0.58) | MAPTKDM4ERPS6KB2NQO2ALDH1A1 | |
| SCHEMBL9979793 | 0.81 | NQO1 (0.36) | MAPTKDM4ERPS6KB2MYCMAX | |
| SCHEMBL3722904 | 0.81 | KDM4E (0.48) | KDM4ERPS6KB2MYCMAXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10454124-B2 | Highly stable phenazine derivatives for aqueous redox flow batteries | BATTELLE MEMORIAL INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
| US-9978474-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-22 | — | — | US | disclosed |
| US-20160247593-A1 | CONDUCTIVE OPEN FRAMEWORKS | UNITED STATES DEPARTMENT OF ENERGY | 2016-08-25 | — | — | US | disclosed |
| US-9269473-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-23 | — | — | US | disclosed |
| WO-2012082213-A2 | CONDUCTIVE OPEN FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160247593-A1 | CONDUCTIVE OPEN FRAMEWORKS | GJB2, OR10J3, EPCAM | MAPT 3871/4885KDM4E 2184/4885RPS6KB2 3039/4885 |
| US-10454124-B2 | Highly stable phenazine derivatives for aqueous redox flow batteries | NDUFS5, NDUFS2, NDUFV1 | MAPT 1172/4885KDM4E 3006/4885RPS6KB2 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.