Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A2 | O43868 | 18/20 | 0.74 |
| ▸ | HSPA8 | P11142 | 4/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2571711 | 1.00 | SLC28A2 (0.74) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL6758906 | 0.95 | SLC28A2 (0.71) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL6758895 | 0.95 | SLC28A2 (0.71) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL13127370 | 0.87 | SLC28A2 (0.69) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL6762482 | 0.87 | ADORA3 (0.63) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL6762488 | 0.87 | ADORA3 (0.63) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL6763669 | 0.85 | ADORA3 (0.61) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL6763667 | 0.85 | ADORA3 (0.61) | SLC28A2HSPA8ADORA3ADORA2A | |
| SCHEMBL31387916 | 0.85 | SLC28A2 (1.00) | SLC28A2HSPA8 | |
| SCHEMBL2574129 | 0.85 | SLC28A2 (1.00) | SLC28A2HSPA8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813623-B1 | PURINENUCLEOSIDE DERIVATIVE MODIFIED IN 8-POSITION AND MEDICINAL USE THEREOF | KISSEI PHARMACEUTICAL (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-20100249054-A9 | PURINE NUCLEOSIDE DERIVATIVE MODIFIED IN 8-POSITION AND MEDICAL USE THEREOF | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| US-7795236-B2 | Purine nucleoside derivative modified in 8-position and medical use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20070179115-A1 | Purinenucleoside derivative modified in 8-position and medical use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1813623-A1 | PURINENUCLEOSIDE DERIVATIVE MODIFIED IN 8-POSITION AND MEDICINAL USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249054-A9 | PURINE NUCLEOSIDE DERIVATIVE MODIFIED IN 8-POSITION AND MEDICAL USE THEREOF | NUDT1, PNP, SLC28A2 | SLC28A2 3/4885HSPA8 2023/4885ADORA3 68/4885 |
| US-20070179115-A1 | Purinenucleoside derivative modified in 8-position and medical use thereof | NUDT1, SLC28A2, PNP | SLC28A2 2/4885HSPA8 1999/4885ADORA3 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.