Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 14/20 | 0.39 |
| ▸ | SLC43A1 | O75387 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619215 | 0.76 | ABCB1 (0.41) | ABCB1SLC43A1TSHRKMT2A | |
| SCHEMBL18511798 | 0.75 | ABCB1 (0.40) | ABCB1SLC43A1TSHRKMT2A | |
| SCHEMBL20725039 | 0.74 | ABCB1 (0.41) | ABCB1 | |
| SCHEMBL20725067 | 0.70 | ABCB1 (0.38) | ABCB1SLC43A1 | |
| SCHEMBL6098797 | 0.69 | LMNA (0.38) | ABCB1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL881993 | 0.69 | LMNA (0.38) | ABCB1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL22742954 | 0.69 | LMNA (0.38) | ABCB1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL882327 | 0.69 | LMNA (0.38) | ABCB1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL6975398 | 0.69 | ABCB1 (0.41) | ABCB1SLC43A1TSHRKMT2A | |
| SCHEMBL6972631 | 0.69 | ABCB1 (0.41) | ABCB1SLC43A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |