Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 19/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SLC43A1 | O75387 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20725068 | 0.89 | ABCB1 (0.37) | ABCB1PTPN1SLC43A1 | |
| SCHEMBL20725039 | 0.81 | ABCB1 (0.41) | ABCB1 | |
| SCHEMBL25716779 | 0.78 | ALDH1A1 (0.41) | ABCB1PTPN1SLC43A1 | |
| SCHEMBL20725069 | 0.74 | — | — | |
| SCHEMBL23619215 | 0.73 | ABCB1 (0.41) | ABCB1SLC43A1 | |
| SCHEMBL18511798 | 0.72 | ABCB1 (0.40) | ABCB1SLC43A1 | |
| SCHEMBL25717634 | 0.70 | ABCB1 (0.39) | ABCB1SLC43A1 | |
| SCHEMBL6975398 | 0.69 | ABCB1 (0.41) | ABCB1SLC43A1 | |
| SCHEMBL6972631 | 0.69 | ABCB1 (0.41) | ABCB1SLC43A1 | |
| SCHEMBL25718276 | 0.68 | P2RY2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202411-B2 | 3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV | IDENIX PHARMACEUTICALS LLC (US) | 2019-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202411-B2 | 3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV | RB1, NSUN2, METTL3 | ABCB1 2042/4885PTPN1 520/4885SLC43A1 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.