Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK3 | P07288 | 9/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.51 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2568841 | 0.89 | KLK3 (0.64) | KLK3MAPTF2KMT2AKLK7 | |
| SCHEMBL2567843 | 0.85 | KLK3 (0.67) | KLK3MAPTF2KMT2AKLK7 | |
| SCHEMBL2561567 | 0.81 | KLK3 (0.56) | KLK3MAPTF2KMT2AKLK7 | |
| SCHEMBL14689119 | 0.78 | F2 (0.55) | MAPTF2KMT2ANPC1RAB9A | |
| SCHEMBL2567005 | 0.76 | F2 (0.58) | MAPTF2KMT2ANPC1RAB9A | |
| SCHEMBL2551230 | 0.74 | KLK3 (0.52) | KLK3MAPTF2KMT2AF12 | |
| SCHEMBL2689845 | 0.71 | CYP2A6 (0.54) | KLK3ALDH1A1 | |
| SCHEMBL2562182 | 0.71 | F2 (0.52) | MAPTF2KMT2AABL1BCR | |
| SCHEMBL18670967 | 0.70 | HDAC1 (0.82) | HDAC1 | |
| SCHEMBL2553680 | 0.70 | MAPT (0.77) | MAPTF2KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560966-A2 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS INHIBITORS OF THROMBIN | Verseon Corporation (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011126903-A2 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS INHIBITORS OF THROMBIN | VERSEON, INC. (US) | 2011-10-13 | — | — | WO | disclosed |