Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL25251702 | 0.91 | MAPK1 (0.43) | MAPK1PARP1MEN1KMT2AL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL30449151 | 0.91 | MAPK1 (0.43) | MAPK1PARP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL21088880 | 0.83 | EPHX2 (0.39) | MAPK1PARP1MEN1KMT2ACD274 | |
| SCHEMBL2644039 | 0.82 | VNN1 (0.53) | MEN1KMT2AKDM4EHDAC1CHEK1 | |
| SCHEMBL21088781 | 0.80 | P4HTM (0.50) | MAPK1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL7883731 | 0.78 | MAPK1 (0.62) | MAPK1PARP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2734359 | 0.77 | HDAC1 (0.55) | MEN1KMT2AHDAC1CHEK1RAB9A | |
| SCHEMBL8324962 | 0.77 | MAPK1 (0.61) | MAPK1PARP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11049864 | 0.76 | MAPK1 (0.49) | MAPK1PARP1KMT2AL3MBTL1KDM4E | |
| SCHEMBL20312849 | 0.75 | CD274 (0.57) | MAPK1PARP1L3MBTL1KDM4ECD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091565-A1 | NSD2-TARGETED CHEMICAL DEGRADERS AND COMPOSITIONS AND METHODS OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-05-25 | — | — | WO | disclosed |