Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PPM1D | O15297 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24501221 | 0.83 | MAPK1 (0.49) | MAPK1PARP1TDP1POLBKMT2A | |
| SCHEMBL11045319 | 0.82 | KDM4E (0.56) | TDP1KMT2AHDAC6KDM4EL3MBTL1 | |
| SCHEMBL11059897 | 0.82 | KDM4E (0.56) | TDP1KMT2AHDAC6KDM4EL3MBTL1 | |
| SCHEMBL11045604 | 0.81 | SMN1; SMN2 (0.41) | GCKTDP1POLBKMT2AHDAC6 | |
| SCHEMBL1698854 | 0.79 | GPR119 (0.57) | KDM4EALDH1A1LMNAHRH3 | |
| SCHEMBL11059205 | 0.79 | GCK (0.36) | MAPK1PARP1GCKTDP1POLB | |
| SCHEMBL11113049 | 0.78 | ACACB (0.43) | GCKTDP1HPGD | |
| SCHEMBL7883731 | 0.77 | MAPK1 (0.62) | MAPK1PARP1TDP1POLBKMT2A | |
| SCHEMBL11059198 | 0.76 | CHRM2 (0.43) | POLBALDH1A1LMNAHRH3 | |
| SCHEMBL6963348 | 0.76 | LOXL2 (0.54) | TDP1PPM1DPOLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984004302-A1 | SUBSTITUTED PICOLINIC ACIDS, PROCESSES FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1984-11-08 | — | — | WO | disclosed |