Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054540 | 0.91 | HPGD (0.73) | HPGDHSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL25720177 | 0.89 | MEN1 (0.57) | HPGDHSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL25720195 | 0.85 | HSP90AA1 (0.53) | HPGDHSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL25720792 | 0.84 | HSP90AA1 (0.59) | HPGDHSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL25720827 | 0.83 | KMT2A (0.51) | HPGDHSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL25720179 | 0.82 | HSP90AA1 (0.77) | HPGDHSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL25720176 | 0.81 | HSP90AA1 (0.63) | HPGDHSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL25720873 | 0.79 | MEN1 (0.47) | HPGDHSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL25720189 | 0.79 | HSP90AA1 (0.49) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL25720137 | 0.78 | SHMT2 (0.52) | HPGDHSD17B10MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | STEMSYNERGY THERAPEUTICS, INC. | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | NOTCH1, NOTCH2, NOTCH4 | HPGD 2805/4885HSD17B10 2619/4885MEN1 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.