Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25720179 | 0.90 | HSP90AA1 (0.77) | HSP90AA1ALOX15HTTKDM4ELMNA | |
| SCHEMBL25722601 | 0.89 | HSP90AA1 (0.79) | HSP90AA1ALOX15HTTKDM4ELMNA | |
| SCHEMBL25720792 | 0.84 | HSP90AA1 (0.59) | HSP90AA1ALOX15HTTKDM4ELMNA | |
| SCHEMBL25720195 | 0.82 | HSP90AA1 (0.53) | HSP90AA1ALOX15HTTKDM4ELMNA | |
| SCHEMBL25720105 | 0.82 | LMNA (0.49) | HTTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL25720201 | 0.81 | HPGD (0.60) | HSP90AA1ALOX15HTTKDM4ELMNA | |
| SCHEMBL25720177 | 0.81 | MEN1 (0.57) | HSP90AA1ALOX15HTTKDM4ELMNA | |
| SCHEMBL25720137 | 0.80 | SHMT2 (0.52) | HSP90AA1ALOX15HTTKDM4ELMNA | |
| SCHEMBL25720189 | 0.78 | HSP90AA1 (0.49) | HSP90AA1ALOX15HTTKDM4ELMNA | |
| SCHEMBL25720447 | 0.77 | HSP90AA1 (1.00) | HSP90AA1ALOX15HTTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | STEMSYNERGY THERAPEUTICS, INC. | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | NOTCH1, NOTCH2, NOTCH4 | HSP90AA1 4749/4885ALOX15 1130/4885HTT 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.