Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.52 |
| ▸ | TTK | P33981 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17088191 | 0.83 | ALDH1A1 (0.52) | TTKMAPTKDM4ETDP1CYP3A4 | |
| SCHEMBL25720323 | 0.83 | FGFR2 (0.44) | S1PR1TTKFGFR2FGFR3GAA | |
| SCHEMBL25418869 | 0.82 | EGFR (0.43) | TTKMAPK14BRAFNTRK1FGFR2 | |
| SCHEMBL31481576 | 0.82 | EGFR (0.43) | TTKMAPK14BRAFNTRK1FGFR2 | |
| SCHEMBL31481543 | 0.81 | EGFR (0.50) | S1PR1MAPK14BRAFNTRK1FGFR2 | |
| SCHEMBL25419956 | 0.81 | MEN1 (0.51) | MAPTKDM4ETHRBTDP1EGFR | |
| SCHEMBL31481571 | 0.81 | MEN1 (0.51) | MAPTKDM4ETHRBTDP1EGFR | |
| SCHEMBL25418273 | 0.81 | EGFR (0.50) | S1PR1MAPK14BRAFNTRK1FGFR2 | |
| SCHEMBL5496607 | 0.78 | GRM4 (0.51) | TTKMAPK14NTRK1FGFR2FGFR3 | |
| SCHEMBL25199043 | 0.78 | CYP11B1 (0.54) | EGFRROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091873-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-25 | — | — | WO | disclosed |