Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 8/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | XBP1 | P17861 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054797 | 0.83 | MAPT (0.68) | ALDH1A1PKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24054800 | 0.82 | MAPT (0.60) | ALDH1A1PKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3411549 | 0.78 | NPC1 (0.49) | ALDH1A1PKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13597944 | 0.76 | ALDH1A1 (1.00) | ALDH1A1PKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13597943 | 0.76 | ALDH1A1 (0.80) | ALDH1A1PKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24054802 | 0.76 | KDM4E (0.70) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL13597951 | 0.75 | RAB9A (0.60) | ALDH1A1PKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13597941 | 0.74 | RAB9A (0.73) | ALDH1A1PKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13597924 | 0.74 | ALDH1A1 (0.71) | ALDH1A1PKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13597938 | 0.74 | RAB9A (0.67) | ALDH1A1PKMRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | STEMSYNERGY THERAPEUTICS, INC. | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | NOTCH1, NOTCH2, NOTCH4 | ALDH1A1 2288/4885PKM 4774/4885RAB9A 1874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.