Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25722152 | 1.00 | DUT (0.38) | DUTMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25727731 | 1.00 | DUT (0.38) | DUTMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25718625 | 0.87 | CYP3A4 (0.41) | DUTMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25723712 | 0.80 | CYP3A4 (0.45) | DUTMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25721246 | 0.80 | CYP3A4 (0.45) | DUTMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25711302 | 0.79 | MEN1 (0.41) | DUTMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25726180 | 0.79 | CYP3A4 (0.47) | DUTMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25710493 | 0.79 | CYP3A4 (0.47) | DUTMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25710332 | 0.79 | CYP3A4 (0.47) | DUTMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25895698 | 0.79 | DUT (0.45) | DUTMEN1KMT2AP2RY2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |