Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | CBFB | Q13951 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 7/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074309 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24075252 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1171206 | 0.78 | ALDH1A1 (0.67) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24075329 | 0.78 | KDM4E (0.68) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24075326 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24075192 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24074350 | 0.76 | NPBWR1 (0.59) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24075057 | 0.75 | KDM4E (0.62) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16121162 | 0.75 | KDM4E (0.55) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24075325 | 0.75 | KDM4E (0.73) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | EPHX1, EPHX2, NCEH1 | KDM4E 1761/4885ALDH1A1 588/4885CYP1A2 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.