Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.36 |
| ▸ | NSD2 | O96028 | 5/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24733364 | 0.89 | DRD2 (0.40) | CTSKUCHL1USP30DRD2DRD3 | |
| SCHEMBL26890036 | 0.87 | CTSK (0.37) | CTSKHRH3UCHL1USP30DRD2 | |
| SCHEMBL26897877 | 0.87 | CTSK (0.37) | CTSKHRH3UCHL1USP30DRD2 | |
| SCHEMBL24733366 | 0.81 | NSD2 (0.36) | CTSKHRH3NSD2KDM1ADRD2 | |
| SCHEMBL2738327 | 0.75 | HRH3 (0.39) | HRH3KDM1AALDH1A1 | |
| SCHEMBL2737372 | 0.75 | HRH3 (0.39) | HRH3KDM1AALDH1A1 | |
| SCHEMBL13995044 | 0.75 | HRH3 (0.39) | HRH3KDM1AALDH1A1 | |
| SCHEMBL25103795 | 0.74 | HRH3 (0.33) | HRH3NSD2KDM1ADRD2DRD3 | |
| SCHEMBL19756477 | 0.74 | HRH3 (0.35) | HRH3NSD2KDM1ADRD2DRD3 | |
| SCHEMBL24649001 | 0.74 | HRH3 (0.38) | HRH3KDM1AALDH1A1SLC6A5KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114428-A1 | HETEROCYCLE DERIVATIVES FOR THE TREATMENT OF DISEASE | Vir Biotechnology, Inc. (US) | 2023-06-22 | — | — | WO | disclosed |