Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.46 |
| ▸ | PRKDC | P78527 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PARG | Q86W56 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25724006 | 0.99 | PIK3CA (0.46) | PIK3CAPRKDCALDH1A1MTORKDM4E | |
| SCHEMBL25724012 | 0.91 | ALDH1A1 (0.41) | PIK3CAPRKDCALDH1A1PARGPDE7A | |
| SCHEMBL25724066 | 0.81 | PARG (0.44) | ALDH1A1PARG | |
| SCHEMBL31135597 | 0.80 | ALDH1A1 (0.51) | PIK3CAPRKDCALDH1A1KDM4EMAPT | |
| SCHEMBL25424313 | 0.80 | ALDH1A1 (0.51) | PIK3CAPRKDCALDH1A1KDM4EMAPT | |
| SCHEMBL17434290 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTGFERTDP1 | |
| SCHEMBL25439300 | 0.77 | PARG (0.46) | ALDH1A1KDM4EMAPTGFERPARG | |
| SCHEMBL30478144 | 0.76 | PARG (0.46) | ALDH1A1KDM4EPARGGAA | |
| SCHEMBL25422664 | 0.76 | PARG (0.46) | ALDH1A1KDM4EPARGGAA | |
| SCHEMBL30478124 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTGFERPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023119320-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-06-29 | — | — | WO | disclosed |