Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 7/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.38 |
| ▸ | PDE8A | O60658 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | PARG | Q86W56 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25724010 | 0.91 | PIK3CA (0.46) | ALDH1A1PDE7AOPRL1OPRM1OPRD1 | |
| SCHEMBL25724006 | 0.90 | PIK3CA (0.46) | ALDH1A1PDE7AOPRL1OPRM1OPRD1 | |
| SCHEMBL25724305 | 0.79 | PARG (0.44) | ALDH1A1PARG | |
| SCHEMBL25724066 | 0.79 | PARG (0.44) | ALDH1A1PARG | |
| SCHEMBL25424313 | 0.79 | ALDH1A1 (0.51) | ALDH1A1PIK3CAPRKDCPARG | |
| SCHEMBL31135597 | 0.79 | ALDH1A1 (0.51) | ALDH1A1PIK3CAPRKDCPARG | |
| SCHEMBL25724415 | 0.77 | PARG (0.43) | ALDH1A1PIK3CAPARG | |
| SCHEMBL17434290 | 0.77 | ALDH1A1 (0.55) | ALDH1A1PARG | |
| SCHEMBL30478100 | 0.76 | TP53 (0.48) | ALDH1A1PDE7APIK3CAPRKDCATM | |
| SCHEMBL25283233 | 0.76 | TP53 (0.48) | ALDH1A1PDE7APIK3CAPRKDCATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023119320-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-06-29 | — | — | WO | disclosed |