⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18408663 | 0.73 | MAPT (0.34) | — | |
| SCHEMBL22328049 | 0.73 | METAP2 (0.33) | — | |
| SCHEMBL22924099 | 0.72 | — | — | |
| SCHEMBL22924101 | 0.71 | — | — | |
| SCHEMBL22924114 | 0.68 | METAP2 (0.36) | — | |
| SCHEMBL24592387 | 0.66 | — | — | |
| SCHEMBL22924128 | 0.62 | — | — | |
| SCHEMBL24089316 | 0.62 | — | — | |
| SCHEMBL22349086 | 0.62 | KDR (0.37) | — | |
| SCHEMBL26522473 | 0.61 | NOS1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203060-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2023-06-29 | — | — | US | disclosed |