Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26272332 | 0.82 | SLC6A2 (0.45) | KDM1AMAOAMAOBSLC13A5HTR2A | |
| SCHEMBL12089063 | 0.78 | CHRM2 (0.38) | KDM1AMAOBHTR2ACYP2D6HRH1 | |
| SCHEMBL14983860 | 0.77 | KDM1A (0.43) | KDM1AMAOAMAOBSLC13A5HTR2A | |
| SCHEMBL19465 | 0.77 | HTR2A (0.46) | KDM1AMAOAMAOBSLC13A5HTR2A | |
| SCHEMBL12089224 | 0.75 | LMNA (0.44) | CYP2D6CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL24225560 | 0.75 | SLC13A5 (0.48) | KDM1AMAOAMAOBSLC13A5HTR2A | |
| SCHEMBL91503 | 0.74 | SLC13A5 (0.50) | KDM1AMAOAMAOBSLC13A5HTR2A | |
| SCHEMBL17570342 | 0.74 | KMT2A (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL25733514 | 0.74 | SLC13A5 (0.36) | SLC13A5CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL12088736 | 0.74 | CHRM2 (0.56) | MAOBCHRM2CHRM1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114428-A1 | HETEROCYCLE DERIVATIVES FOR THE TREATMENT OF DISEASE | Vir Biotechnology, Inc. (US) | 2023-06-22 | — | — | WO | disclosed |