SCHEMBL91503

SCHEMBL91503

CCc1cccnc1OC

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC13A5 Q86YT5 3/20 0.50
KDM1A O60341 5/20 0.47
MAOA P21397 2/20 0.47
MAOB P27338 1/20 0.47
APLNR P35414 1/20 0.44
BTK Q06187 1/20 0.44
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
DRD1 P21728 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SSTR4 P31391 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6588356 0.86 SLC13A5 (0.49) SLC13A5KDM1AMAOAMAOBAPLNR
SCHEMBL12093550 0.84 SLC13A5 (0.51) SLC13A5KDM1AMAOAMAOBAPLNR
SCHEMBL8116304 0.83 BTK (0.49) SLC13A5KDM1AMAOAMAOBBTK
SCHEMBL12948866 0.83 SLC13A5 (0.52) SLC13A5L3MBTL1NPC1SSTR4
SCHEMBL27585504 0.82 KDM1A (0.41) SLC13A5KDM1AMAOAMAOBAPLNR
SCHEMBL18291875 0.82 SLC13A5 (0.49) SLC13A5KDM1AMAOAMAOBAPLNR
SCHEMBL2960548 0.82 SLC13A5 (0.49) SLC13A5KDM1AMAOAMAOBAPLNR
SCHEMBL129593 0.82 KDM1A (0.46) SLC13A5KDM1AMAOAMAOBAPLNR
SCHEMBL19465 0.82 HTR2A (0.46) SLC13A5KDM1AMAOAMAOBAPLNR
SCHEMBL31365171 0.82 MEN1 (0.60) SLC13A5KDM1AMAOAMAOBAPLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116854626-A Preparation method of 2-vinyl pyridine 河南省科学院高新技术研究中心 2023-10-10 CN claimed
CN-116854626-B Preparation method of 2-vinyl pyridine 河南省科学院高新技术研究中心 2025-10-28 CN disclosed
CN-119977873-A Method for synthesizing 2-vinyl pyridine by one-pot method 南京红太阳生物化学有限责任公司 2025-05-13 CN disclosed
US-20240018115-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE LOXO ONCOLOGY, INC. 2024-01-18 US disclosed
CN-116854626-A Preparation method of 2-vinyl pyridine 河南省科学院高新技术研究中心 2023-10-10 CN disclosed
CN-116854626-A Preparation method of 2-vinyl pyridine 河南省科学院高新技术研究中心 2023-10-10 CN disclosed
US-11771738-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-03 US disclosed
US-20230303570-A1 KINASE INHIBITORS AND USES THEREOF ABM THERAPEUTICS CORP (US) 2023-09-28 US disclosed
US-11753393-B2 Dihydroorotate dehydrogenase inhibitors JANSSEN BIOTECH, INC. 2023-09-12 US disclosed
US-11739077-B2 Small molecule inhibitors of ubiquitin specific protease 1 (USP1) and uses thereof INSILICO MEDICINE IP LIMITED (HK) 2023-08-29 US disclosed
US-7514452-B2 2-furancarboxylic acid hydrazides and pharmaceutical compositions containing the same DAINIPPON PHARMACEUTICAL CO., LTD (JP) 2009-04-07 US disclosed
US-20090054423-A1 Niacin receptor agonists, compositions containing such compounds and methods of treatment MERCK SHARP & DOHME CORP. 2009-02-26 US disclosed
US-20080312435-A1 Imine Compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2008-12-18 US disclosed
US-20080280925-A1 Amines as Small Molecule Inhibitors METHYLGENE INC. 2008-11-13 US disclosed
US-20080132503-A1 Inhibitors of Histone Deacetylase METHYLGENE INC. (CA) 2008-06-05 US disclosed
WO-2008008374-A2 CCR2 INHIBITORS AND METHODS OF USE THEREOF CHEMOCENTRYX, INC. (US) 2008-01-17 WO disclosed
US-20080004282-A1 Compositions and methods for modulating gated ion channels PAINCEPTOR PHARMA CORPORATION (CA) 2008-01-03 US disclosed
US-20070264196-A1 Modulators of ATP-binding cassette transporters VERTEX PHARMACEUTICALS INCORPORATED 2007-11-15 US disclosed
US-20070225365-A1 Cetp Inhibitors MERCK & CO., INC. (US) 2007-09-27 US disclosed
US-20070027321-A1 Bipyridyl amines and ethers as modulators of metabotropic glutamate receptor-5 MERCK SHARP & DOHME CORP. 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303570-A1 KINASE INHIBITORS AND USES THEREOF ERBB2, ERBB3, ERBB4 SLC13A5 4851/4885KDM1A 1993/4885MAOA 2096/4885
US-20080312435-A1 Imine Compound CNR1, CNR2, HRH4 SLC13A5 3061/4885KDM1A 2503/4885MAOA 2501/4885
US-20080280925-A1 Amines as Small Molecule Inhibitors CARM1, PRMT1, PRMT3 SLC13A5 2407/4885KDM1A 105/4885MAOA 569/4885
US-11753393-B2 Dihydroorotate dehydrogenase inhibitors DHODH, DLD, DPYD SLC13A5 1694/4885KDM1A 1067/4885MAOA 368/4885
US-20070225365-A1 Cetp Inhibitors CETP, APOB, NPC1 SLC13A5 2589/4885KDM1A 1488/4885MAOA 1565/4885
US-20240018115-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PIK3CA, PIK3R4, PIK3R5 SLC13A5 3294/4885KDM1A 3056/4885MAOA 2964/4885
US-20070264196-A1 Modulators of ATP-binding cassette transporters CFTR, ABCB1, ABCC2 SLC13A5 641/4885KDM1A 4611/4885MAOA 3866/4885
US-20080004282-A1 Compositions and methods for modulating gated ion channels KCNN3, KCNN2, HCN3 SLC13A5 990/4885KDM1A 3078/4885MAOA 1975/4885
US-20070027321-A1 Bipyridyl amines and ethers as modulators of metabotropic glutamate receptor-5 GRM5, GRIK5, GRM1 SLC13A5 2769/4885KDM1A 722/4885MAOA 3224/4885
US-11771738-B2 Endoparasitic depsipeptides VIP, PREP, VIPR1 SLC13A5 1616/4885KDM1A 2133/4885MAOA 4400/4885
US-20090054423-A1 Niacin receptor agonists, compositions containing such compounds and methods of treatment FFAR1, HCAR1, GPR119 SLC13A5 257/4885KDM1A 4370/4885MAOA 860/4885
US-20080132503-A1 Inhibitors of Histone Deacetylase HDAC1, HDAC5, HDAC3 SLC13A5 4575/4885KDM1A 41/4885MAOA 1961/4885
US-11739077-B2 Small molecule inhibitors of ubiquitin specific protease 1 (USP1) and uses thereof USP1, USP2, USP28 SLC13A5 4751/4885KDM1A 205/4885MAOA 2794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.