Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | PARG | Q86W56 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25724310 | 0.86 | ALDH1A1 (0.43) | ADORA2BPARGALDH1A1KDM4EGAA | |
| SCHEMBL17434477 | 0.80 | PARG (0.57) | ADORA2BPARGALDH1A1TSHRKDM4E | |
| SCHEMBL17434290 | 0.80 | ALDH1A1 (0.55) | ADORA2BPARGALDH1A1TSHRKDM4E | |
| SCHEMBL25439300 | 0.78 | PARG (0.46) | ADORA2BPARGALDH1A1TSHRKDM4E | |
| SCHEMBL25425477 | 0.78 | KMT2A (0.47) | ADORA2BALDH1A1TSHRKDM4EGAA | |
| SCHEMBL25724305 | 0.78 | PARG (0.44) | ADORA2BPARGALDH1A1 | |
| SCHEMBL25422664 | 0.78 | PARG (0.46) | ADORA2BPARGALDH1A1TSHRKDM4E | |
| SCHEMBL30478144 | 0.78 | PARG (0.46) | ADORA2BPARGALDH1A1TSHRKDM4E | |
| SCHEMBL25424313 | 0.77 | ALDH1A1 (0.51) | ADORA2BPARGALDH1A1KDM4EGAA | |
| SCHEMBL31135597 | 0.77 | ALDH1A1 (0.51) | ADORA2BPARGALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023119320-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-06-29 | — | — | WO | disclosed |