Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | PARG | Q86W56 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25724307 | 0.86 | ADORA2B (0.42) | ALDH1A1PARGADORA2BPDE4AADORA2A | |
| SCHEMBL17434290 | 0.84 | ALDH1A1 (0.55) | ALDH1A1PARGMEN1KMT2AADORA2B | |
| SCHEMBL17434477 | 0.84 | PARG (0.57) | ALDH1A1PARGMEN1KMT2AADORA2B | |
| SCHEMBL25724379 | 0.83 | CDK4 (0.41) | ALDH1A1PARGMEN1KMT2AADORA2B | |
| SCHEMBL25439300 | 0.83 | PARG (0.46) | ALDH1A1PARGMEN1KMT2AADORA2B | |
| SCHEMBL25724305 | 0.82 | PARG (0.44) | ALDH1A1PARGADORA2B | |
| SCHEMBL25422664 | 0.82 | PARG (0.46) | ALDH1A1PARGADORA2BKDM4EGAA | |
| SCHEMBL30478144 | 0.82 | PARG (0.46) | ALDH1A1PARGADORA2BKDM4EGAA | |
| SCHEMBL25724068 | 0.81 | MEN1 (0.54) | MEN1KMT2AADORA2BMAPTBRD4 | |
| SCHEMBL25424313 | 0.81 | ALDH1A1 (0.51) | ALDH1A1PARGADORA2BPTGER4PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023119320-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-06-29 | — | — | WO | disclosed |