Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17912492 | 0.82 | CA12 (0.47) | MYCL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL8054469 | 0.82 | ACE2 (0.50) | KDM4EMYCL3MBTL1MEN1KMT2A | |
| SCHEMBL3194641 | 0.81 | KDM4E (0.48) | KDM4EGLAMYCNR4A1L3MBTL1 | |
| SCHEMBL29005696 | 0.80 | KDM4E (0.47) | KDM4EGLAMYCNR4A1L3MBTL1 | |
| SCHEMBL27961101 | 0.76 | ALDH1A1 (0.46) | KDM4EMYCNR4A1L3MBTL1KMT2A | |
| SCHEMBL11613901 | 0.75 | KDM4E (0.50) | KDM4EGLAMYCNR4A1MEN1 | |
| SCHEMBL3201674 | 0.75 | KDM4E (0.43) | KDM4EGLAMYCNR4A1L3MBTL1 | |
| SCHEMBL17187941 | 0.75 | KDM4E (0.43) | KDM4EGLAMYCNR4A1L3MBTL1 | |
| SCHEMBL257228 | 0.74 | KDM4E (0.48) | KDM4EGLAMYCNR4A1MEN1 | |
| SCHEMBL6132146 | 0.73 | CYP1A2 (0.41) | MEN1KMT2AMAPTALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029942-A1 | CYCLIC AMIDE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2012-03-08 | — | — | WO | disclosed |