Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 8/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194641 | 0.87 | KDM4E (0.48) | KDM4EGLAMYCNR4A1GRIN1 | |
| SCHEMBL11613901 | 0.85 | KDM4E (0.50) | KDM4EGLAMYCNR4A1GRIN1 | |
| SCHEMBL28007033 | 0.81 | CSNK2A1 (0.48) | ALDH1A1MEN1KMT2AACE2POLB | |
| SCHEMBL3201674 | 0.81 | KDM4E (0.43) | KDM4EGLAMYCNR4A1L3MBTL1 | |
| SCHEMBL17187941 | 0.81 | KDM4E (0.43) | KDM4EGLAMYCNR4A1GRIN1 | |
| SCHEMBL12095472 | 0.81 | NR4A2 (0.48) | KDM4EGLAL3MBTL1ALDH1A1 | |
| SCHEMBL257251 | 0.80 | KDM4E (0.42) | KDM4EGLAMYCNR4A1GRIN1 | |
| SCHEMBL257228 | 0.79 | KDM4E (0.48) | KDM4EGLAMYCNR4A1GRIN1 | |
| SCHEMBL28759823 | 0.77 | SMN1; SMN2 (0.49) | KDM4EL3MBTL1ALDH1A1RXFP1MEN1 | |
| SCHEMBL31502427 | 0.76 | ALDH1A1 (0.42) | KDM4EGLAMYCNR4A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| CN-115996926-A | Indole compounds as androgen receptor modulators | 尼多生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |