Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | USP2 | O75604 | 5/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25633293 | 0.89 | HTT (0.52) | AURKAHTTKITALDH1A1MEN1 | |
| SCHEMBL25630561 | 0.86 | KIT (0.41) | AURKAHTTKITALDH1A1CYP1A2 | |
| SCHEMBL25229702 | 0.86 | AKT1 (0.44) | AURKAKIT | |
| SCHEMBL25227852 | 0.86 | HTT (0.44) | AURKAHTTKITALDH1A1CYP1A2 | |
| SCHEMBL31501711 | 0.86 | HTT (0.44) | AURKAHTTKITALDH1A1CYP1A2 | |
| SCHEMBL25716737 | 0.83 | HTT (0.46) | HRH4HTTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25633496 | 0.82 | CYP1A2 (0.42) | HRH4HTTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25225988 | 0.82 | KIT (0.49) | KITCYP3A4USP2CYP2C19HSD17B10 | |
| SCHEMBL30455937 | 0.82 | KIT (0.49) | KITCYP3A4USP2CYP2C19HSD17B10 | |
| SCHEMBL25725472 | 0.81 | HRH4 (0.69) | HRH4HTTKITALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |