SCHEMBL2572575

SCHEMBL2572575

CCCCCCOc1c(Br)ccc2c(OCCCCCC)c(Br)ccc12

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRA P10827 4/20 0.49
THRB P10828 4/20 0.49
NR5A1 Q13285 1/20 0.44
S1PR2 O95136 4/20 0.40
S1PR1 P21453 4/20 0.40
S1PR3 Q99500 4/20 0.40
LPAR2 Q9HBW0 3/20 0.40
TLR4 O00206 2/20 0.40
TSHR P16473 2/20 0.40
TP53 P04637 1/20 0.40
FAAH O00519 1/20 0.39
MGLL Q99685 1/20 0.39
LTA4H P09960 2/20 0.39
PLA2G4B P0C869 1/20 0.39
S1PR4 O95977 2/20 0.38
S1PR5 Q9H228 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2957901 1.00 THRA (0.49) THRATHRBNR5A1S1PR2S1PR1
SCHEMBL19462419 0.93 THRA (0.44) THRATHRBNR5A1S1PR2S1PR1
SCHEMBL5793269 0.92 THRA (0.51) THRATHRBNR5A1S1PR2S1PR1
SCHEMBL10356794 0.88 THRA (0.43) THRATHRBNR5A1S1PR2S1PR1
SCHEMBL10357578 0.86 THRA (0.42) THRATHRBNR5A1S1PR2S1PR1
SCHEMBL16515988 0.85 ALDH1A1 (0.42) THRATHRBTLR4TSHRLTA4H
SCHEMBL28393826 0.84 THRA (0.53) THRATHRBNR5A1S1PR2S1PR1
SCHEMBL2954021 0.84 THRA (0.43) THRATHRBNR5A1S1PR2S1PR1
SCHEMBL28558627 0.82 THRA (0.44) THRATHRBNR5A1S1PR2S1PR1
SCHEMBL2258572 0.82 THRA (0.44) THRATHRBNR5A1S1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1213336-B1 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL CO (JP) 2011-11-09 EP disclosed
US-7750112-B2 Polymers comprising benzotriazole for use in optical devices CIBA SPECIALTY CHEMICALS CORP. (US) 2010-07-06 US disclosed
US-7701129-B2 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-20 US disclosed
US-7348071-B2 Complex fluorene-containing compounds and use EASTMAN KODAK COMPANY (US) 2008-03-25 US disclosed
US-20070287821-A1 Synthesis of Polynaphthalenes and Their Use BASF AKTIENGESELLSCHAFT (DE) 2007-12-13 US disclosed
US-20070287821-A1 Synthesis of Polynaphthalenes and Their Use BASF AKTIENGESELLSCHAFT (DE) 2007-12-13 US disclosed
US-7285341-B2 Complex fluorene-containing compounds for use in OLED devices EASTMAN KODAK COMPANY (US) 2007-10-23 US disclosed
EP-1791889-A1 SYNTHESIS OF POLYNAPHTHALENES AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2007-06-06 EP disclosed
US-20070043204-A1 Novel polymers comprising benzotriazole for use in optical devices CIBA SPECIALITY CHEMICALS CORP. 2007-02-22 US disclosed
WO-2006027191-A1 SYNTHESIS OF POLYNAPHTHALENES AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2006-03-16 WO disclosed
EP-1088875-B1 Electroluminescent devices having phenylanthracene-based polymers EASTMAN KODAK CO (US) 2003-11-26 EP disclosed
EP-1164178-B1 Electroluminescent devices having arylamine polymers EASTMAN KODAK CO (US) 2003-09-03 EP disclosed
US-20020122899-A1 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-09-05 US disclosed
EP-1213336-A2 Polymeric fluorescent substance and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-12 EP disclosed
EP-1164178-A1 Electroluminescent devices having arylamine polymers EASTMAN KODAK COMPANY (US) 2001-12-19 EP disclosed
US-6329086-B1 GOOD SOLUBILITY, EFFICIENCY AND STABILITY; EMITTING COLOR OF THE POLYMER CAN BE EASILY TUNED BY THE INCORPORATION OF DESIRED AROMATIC GROUP; POLYARYLENEVINYLENE EASTMAN KODAK COMPANY 2001-12-11 US disclosed
US-6268072-B1 AROMATIC RESIN EASTMAN KODAK COMPANY 2001-07-31 US disclosed
EP-1088875-A2 Electroluminescent devices having phenylanthracene-based polymers EASTMAN KODAK COMPANY (US) 2001-04-04 EP disclosed