Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422050 | 0.89 | RAB9A (0.56) | TP53NPC1RAB9APKMAKR1C3 | |
| SCHEMBL9422052 | 0.89 | RAB9A (0.56) | TP53NPC1RAB9APKMAKR1C3 | |
| SCHEMBL7271917 | 0.86 | SRD5A2 (0.60) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL95646 | 0.86 | TP53 (0.57) | TP53NPC1RAB9APKMMEN1 | |
| SCHEMBL23070442 | 0.85 | HPGD (0.53) | TP53NPC1RAB9APKMMEN1 | |
| SCHEMBL10774999 | 0.84 | MAPT (0.50) | TP53NPC1RAB9APKMKMT2A | |
| SCHEMBL11363696 | 0.84 | TP53 (0.50) | TP53NPC1RAB9APKMMEN1 | |
| SCHEMBL7208739 | 0.84 | RAB9A (0.59) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL28384878 | 0.83 | AKR1C3 (0.61) | TP53NPC1PKMMEN1KMT2A | |
| SCHEMBL29826380 | 0.83 | AKR1C3 (0.57) | NPC1RAB9APKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970976-A | The polysilsesquioxane and its preparation method and application of tetraphenylethylene base bridging | 苏州大学 | 2019-07-05 | — | — | CN | claimed |
| CN-115960483-A | Method for reducing shrinkage stress of photocureable coating by using pH-responsive cationic microgel | 江南大学 | 2023-04-14 | — | — | CN | disclosed |
| US-8895552-B2 | Cyclic amide derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-8895552-B2 | Cyclic amide derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20130217692-A1 | CYCLIC AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| US-20130217692-A1 | CYCLIC AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| EP-2612848-A1 | CYCLIC AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012029942-A1 | CYCLIC AMIDE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2012-03-08 | — | — | WO | disclosed |
| EP-0480365-B1 | Production of solder masked electric circuit boards | NIPPON PAINT CO LTD (JP) | 1996-01-10 | — | — | EP | disclosed |
| US-5181984-A | PRODUCTION OF SOLDER MASKED ELECTRIC CIRCUIT BOARDS | NIPPON PAINT CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0092628-B1 | PROCESS FOR THE PREPARATION OF PHENYL KETONES STARTING FROM HALOGEN OR TRIHALOGEN METHYL BENZENES AND ALIPHATIC OR AROMATIC TRIHALOGEN-METHYL COMPOUNDS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-05-29 | — | — | EP | disclosed |
| US-4495311-A | METAL CHELATES OR SALTS AND BENZOYL COMPOUNDS AS ADDIVES | PRINCETON POLYMER LABORATORIES, INC. (US) | 1985-01-22 | — | — | US | disclosed |
| US-4347383-A | BY REACTING BENZOPHENONE-IMINE WITH OXYGEN OR BENZOPHENONE WITH OXYGEN AND AMMONIA | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-08-31 | — | — | US | disclosed |
| US-3981856-A | BIODEGRADATION, ADDITION POLYMERS | PRINCETON POLYMER LABORATORIES, INCORPORATED (US) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217692-A1 | CYCLIC AMIDE DERIVATIVE | HDAC10, H1-10, H1-0 | TP53 4509/4885NPC1 1990/4885RAB9A 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.