SCHEMBL257320

SCHEMBL257320

CCCOc1ccc(Cl)cc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.64
S1PR4 O95977 9/20 0.59
MAPT P10636 2/20 0.57
HPGD P15428 4/20 0.56
TSHR P16473 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
ALDH1A1 P00352 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53
MAPK1 P28482 1/20 0.53
CYP2C19 P33261 1/20 0.53
THPO P40225 1/20 0.53
HIF1A Q16665 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5477791 0.90 ALDH1A1 (0.68) CSNK2A1S1PR4MAPTHPGDTSHR
SCHEMBL15894111 0.89 ALDH1A1 (0.61) CSNK2A1S1PR4MAPTHPGDTSHR
SCHEMBL11413525 0.87 S1PR4 (0.66) S1PR4MAPTTDP1
SCHEMBL15894082 0.87 ALDH1A1 (0.60) CSNK2A1S1PR4MAPTHPGDTSHR
SCHEMBL15894081 0.87 ALDH1A1 (0.60) CSNK2A1S1PR4MAPTHPGDTSHR
SCHEMBL3781671 0.86 MAPT (0.54) CSNK2A1S1PR4MAPTHPGDTSHR
SCHEMBL26667637 0.84 ALDH1A1 (0.54) CSNK2A1S1PR4MAPTHPGDTSHR
SCHEMBL1547765 0.83 TDP1 (0.56) S1PR4MAPTHPGDTSHRTDP1
SCHEMBL11423354 0.83 MAPT (0.52) S1PR4MAPTHPGDTSHRTDP1
SCHEMBL3787950 0.82 CSNK2A1 (0.62) CSNK2A1S1PR4MAPTTDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108689867-B Preparation method of 2, 4-dichloro-5-isopropoxy aniline 连云港市金囤农化有限公司 2021-03-30 CN claimed
CN-108689867-B Preparation method of 2, 4-dichloro-5-isopropoxy aniline 连云港市金囤农化有限公司 2021-03-30 CN disclosed
CN-108689867-B Preparation method of 2, 4-dichloro-5-isopropoxy aniline 连云港市金囤农化有限公司 2021-03-30 CN disclosed
CN-105431414-B The 4 round rings formamides as nematicide 先正达参股股份有限公司 2018-06-15 CN disclosed
WO-2012028578-A1 SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES BAYER CROPSCIENCE AG (DE) 2012-03-08 WO disclosed
US-7655689-B2 Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2010-02-02 US disclosed
US-7655689-B2 Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2010-02-02 US disclosed
US-7517904-B2 Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2009-04-14 US disclosed
US-7517904-B2 Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2009-04-14 US disclosed
US-7470797-B2 Fused heterocyclic imido and amido compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2008-12-30 US disclosed
EP-0403883-A1 Herbicidal agents on base of sulfonylated aminoguanidines BAYER AG (DE) 1990-12-27 EP disclosed
EP-0384192-A2 N-Aryl nitrogen heterocycles having fluorine-containing substituents BAYER AG (DE) 1990-08-29 EP disclosed
EP-0369212-A1 Derivatives of (hetero)aryloxynaphthalene, process, and (hetero)aryloxynaphthyl amines, and their use as herbicides BAYER AG (DE) 1990-05-23 EP disclosed
EP-0334055-A2 Substituted benzoxazinones, several processes and intermediates for their preparation and their use as herbicides BAYER AG (DE) 1989-09-27 EP disclosed
EP-0298371-A1 Substituted triazolinones BAYER AG (DE) 1989-01-11 EP disclosed
EP-0282811-A1 4-Cyano-1-aryl-pyrazoles BAYER AG (DE) 1988-09-21 EP disclosed
EP-0278258-A1 Substituted (phenoxy-benzoyloxy)-(pyridyl)-methane (thio)-phosphonic-acid esters, process for their preparation and their use as herbicides BAYER AG (DE) 1988-08-17 EP disclosed
EP-0232538-A2 5-Acylamido-1-aryl pyrazoles BAYER AG (DE) 1987-08-19 EP disclosed
EP-0226837-A2 Pyri(mi)dyloxy and -thiobenzoic acid derivatives BAYER AG (DE) 1987-07-01 EP disclosed
EP-0224094-A2 1-Aryl-pyrazole BAYER AG (DE) 1987-06-03 EP disclosed