Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15894111 | 0.94 | ALDH1A1 (0.61) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL15894082 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL15894081 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL257320 | 0.90 | CSNK2A1 (0.64) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL3794601 | 0.86 | L3MBTL1 (0.53) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL11413525 | 0.86 | S1PR4 (0.66) | TDP1MAPTS1PR4 | |
| SCHEMBL17546739 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL3785500 | 0.85 | SMN1; SMN2 (0.59) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL7237501 | 0.84 | MAPT (0.58) | ALDH1A1TDP1SMN1; SMN2MAPTHPGD | |
| SCHEMBL29435284 | 0.84 | ALDH1A1 (0.78) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168484-A1 | \"COMPOUNDS AND METHODS\ | DemAgtech Pty Ltd (AU) | 2023-09-14 | — | — | WO | disclosed |
| WO-2019179288-A2 | PREPARATION METHOD FOR CHLOROPHENOXYCARBOXYLATE | 山东润博生物科技有限公司 | 2019-09-26 | — | — | WO | disclosed |
| WO-2019179291-A2 | PREPARATION METHOD FOR CHLOROPHENOXYCARBOXYLATE | 山东润博生物科技有限公司 | 2019-09-26 | — | — | WO | disclosed |
| US-9675620-B2 | MAO inhibitors and their conjugates as therapeutics for the treatment of brain cancer | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-06-13 | — | — | US | disclosed |
| US-20170029371-A1 | MAO INHIBITORS AND THEIR CONJUGATES AS THERAPEUTICS FOR THE TREATMENT OF BRAIN CANCER | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-02-02 | — | — | US | disclosed |
| US-20160339034-A9 | MAO Inhibitors and Their Conjugates as Therapeutics For The Treatment of Brain Cancer | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2016-11-24 | — | — | US | disclosed |
| WO-2015129813-A1 | DEUTERATION METHOD AND DEUTERATION CATALYST | 国立大学法人 長崎大学 | 2015-09-03 | — | — | WO | disclosed |
| US-20150209361-A1 | MAO Inhibitors and Their Conjugates as Therapeutics For The Treatment of Brain Cancer | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-07-30 | — | — | US | disclosed |
| WO-2014113495-A1 | ACTIVATION OR REACTIVATION OF ACHE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-07-24 | — | — | WO | disclosed |
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | WYETH | 2007-12-13 | — | — | US | disclosed |
| EP-1817958-A1 | Herbicidal mixtures | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2004002483-A1 | SUBSTITUTED 3- AND 4- AMINOMETHYLPIPERIDINES FOR USE AS BETA-SECRETASE IN THE TREATMENT OF ALZHEIMER’S DISEASE | ACTELION PHARMACEUTICALS LTD (CH) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029371-A1 | MAO INHIBITORS AND THEIR CONJUGATES AS THERAPEUTICS FOR THE TREATMENT OF BRAIN CANCER | MAOA, MAOB, COMT | ALDH1A1 413/4885TDP1 1116/4885L3MBTL1 3733/4885 |
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K6 | ALDH1A1 3084/4885TDP1 966/4885L3MBTL1 2767/4885 |
| US-20150209361-A1 | MAO Inhibitors and Their Conjugates as Therapeutics For The Treatment of Brain Cancer | MAOA, MAOB, COMT | ALDH1A1 413/4885TDP1 1116/4885L3MBTL1 3733/4885 |
| US-20160339034-A9 | MAO Inhibitors and Their Conjugates as Therapeutics For The Treatment of Brain Cancer | MAOA, MAOB, COMT | ALDH1A1 413/4885TDP1 1116/4885L3MBTL1 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.