Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 16/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.43 |
| ▸ | HPGD | P15428 | 15/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 15/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | STK4 | Q13043 | 1/20 | 0.36 |
| ▸ | STK3 | Q13188 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31730888 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL31730928 | 0.92 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL25732826 | 0.92 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL31731044 | 0.84 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL25732831 | 0.84 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL31730961 | 0.83 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL25732813 | 0.83 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL25274610 | 0.81 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL25234661 | 0.79 | KDM4E (0.45) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL25230544 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |