Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.43 |
| ▸ | HPGD | P15428 | 13/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 13/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | STK4 | Q13043 | 1/20 | 0.36 |
| ▸ | STK3 | Q13188 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31731044 | 1.00 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25732827 | 0.92 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL31731024 | 0.92 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL31730888 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25732828 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25279233 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25234661 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL25231072 | 0.80 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL31730880 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL31730862 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |