Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14365691 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL14365743 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL17287129 | 0.81 | MMP1 (0.41) | SMN1; SMN2PKMGAAHTTKMT2A | |
| SCHEMBL9050303 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL13866419 | 0.79 | MMP1 (0.44) | GAAHTTTSHRALDH1A1HPGD | |
| SCHEMBL738198 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL762984 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL2115037 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL5778346 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL13912231 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2PKMCYP3A4CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114428-A1 | HETEROCYCLE DERIVATIVES FOR THE TREATMENT OF DISEASE | Vir Biotechnology, Inc. (US) | 2023-06-22 | — | — | WO | disclosed |