Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866419 | 0.98 | MMP1 (0.44) | MMP1MMP2MMP8HPGDALDH1A1 | |
| SCHEMBL25906054 | 0.86 | MMP1 (0.40) | MMP1MMP2MMP8HPGDALDH1A1 | |
| SCHEMBL25732914 | 0.81 | SMN1; SMN2 (0.52) | HPGDALDH1A1HTTGAAMEN1 | |
| SCHEMBL27469804 | 0.79 | CYP2C9 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12460865 | 0.79 | RAB9A (0.42) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11983556 | 0.79 | ALDH1A1 (0.61) | HPGDALDH1A1POLBGAAMEN1 | |
| SCHEMBL13244080 | 0.79 | L3MBTL1 (0.40) | MMP1MMP2MMP8ALDH1A1HTT | |
| SCHEMBL18526588 | 0.78 | DPP4 (0.49) | MMP1MMP2MMP8HPGDALDH1A1 | |
| SCHEMBL17275494 | 0.78 | HPGD (0.41) | MMP1MMP2MMP8HPGDALDH1A1 | |
| SCHEMBL4239694 | 0.78 | HPGD (0.41) | MMP1MMP2MMP8HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179349-A2 | SYNTHESIS OF BETA-ARRESTIN EFFECTORS | TREVENA, INC. (US) | 2015-11-26 | — | — | WO | disclosed |