Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | USP1 | O94782 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31730853 | 1.00 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGUSP1 | |
| SCHEMBL25733593 | 0.90 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CGMTOR | |
| SCHEMBL31730925 | 0.90 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CGMTOR | |
| SCHEMBL31730860 | 0.88 | HDAC3 (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGMAP3K12 | |
| SCHEMBL25733600 | 0.88 | HDAC3 (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGMAP3K12 | |
| SCHEMBL31730900 | 0.84 | MTOR (0.38) | PIK3CDPIK3CAPIK3CBNPSR1TRPM8 | |
| SCHEMBL25733594 | 0.84 | MTOR (0.38) | PIK3CDPIK3CAPIK3CBNPSR1TRPM8 | |
| SCHEMBL25733410 | 0.78 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CGMTORPIK3R1 | |
| SCHEMBL31730923 | 0.78 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CGMTORPIK3R1 | |
| SCHEMBL25280763 | 0.78 | HDAC1 (0.39) | PIK3CDPIK3CAPIK3CBPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |