Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | MTOR | P42345 | 3/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31730923 | 1.00 | PIK3CD (0.45) | PIK3CDUSP30GPR119PIK3CAMTOR | |
| SCHEMBL25229681 | 0.96 | PIK3CD (0.43) | PIK3CDUSP30GPR119PIK3CAMTOR | |
| SCHEMBL25733559 | 0.96 | GPR119 (0.43) | PIK3CDUSP30GPR119PIK3CAMTOR | |
| SCHEMBL31730879 | 0.96 | GPR119 (0.43) | PIK3CDUSP30GPR119PIK3CAMTOR | |
| SCHEMBL31730860 | 0.90 | HDAC3 (0.40) | PIK3CDPIK3CAPIK3CGHDAC3HDAC4 | |
| SCHEMBL25733600 | 0.90 | HDAC3 (0.40) | PIK3CDPIK3CAPIK3CGHDAC3HDAC4 | |
| SCHEMBL31730925 | 0.89 | PIK3CD (0.42) | PIK3CDUSP30GPR119PIK3CAMTOR | |
| SCHEMBL25733593 | 0.89 | PIK3CD (0.42) | PIK3CDUSP30GPR119PIK3CAMTOR | |
| SCHEMBL31730820 | 0.89 | PIK3CD (0.38) | PIK3CDGPR119PIK3CAMTORPIK3CG | |
| SCHEMBL25280763 | 0.86 | HDAC1 (0.39) | PIK3CDPIK3CAMTORPIK3CGHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |