SCHEMBL31730925

SCHEMBL31730925

Cn1c(-c2ccccn2)nc2c(N3CCOCC3)nc(-n3ccc(C4CCN(C(=O)OC(C)(C)C)C4)n3)nc21

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 12/20 0.42
▸ USP30 Q70CQ3 3/20 0.40
▸ GPR119 Q8TDV5 2/20 0.38
▸ PIK3CA P42336 2/20 0.37
▸ MTOR P42345 1/20 0.37
▸ PIK3CG P48736 1/20 0.37
▸ ATR Q13535 1/20 0.37
▸ AURKB Q96GD4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25733593 1.00 PIK3CD (0.42) PIK3CDUSP30GPR119PIK3CAMTOR
SCHEMBL31730853 0.90 PIK3CD (0.40) PIK3CDPIK3CAMTORPIK3CG
SCHEMBL25733595 0.90 PIK3CD (0.40) PIK3CDPIK3CAMTORPIK3CG
SCHEMBL31730923 0.89 PIK3CD (0.45) PIK3CDUSP30GPR119PIK3CAMTOR
SCHEMBL25733410 0.89 PIK3CD (0.45) PIK3CDUSP30GPR119PIK3CAMTOR
SCHEMBL25229681 0.85 PIK3CD (0.43) PIK3CDUSP30GPR119PIK3CAMTOR
SCHEMBL31730879 0.84 GPR119 (0.43) PIK3CDUSP30GPR119PIK3CAMTOR
SCHEMBL25733559 0.84 GPR119 (0.43) PIK3CDUSP30GPR119PIK3CAMTOR
SCHEMBL25735110 0.82 PIK3CD (0.40) PIK3CDUSP30GPR119PIK3CAMTOR
SCHEMBL25229334 0.81 PIK3CA (0.40) PIK3CDGPR119PIK3CAMTORPIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353851-A1 PURINES AND METHODS OF THEIR USE KINETA INC (US) 2025-11-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353851-A1 PURINES AND METHODS OF THEIR USE TDP1, TDP2, PIKFYVE PIK3CD 138/4885USP30 3228/4885GPR119 1751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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